Lipids and Atherogenic Indices Fluctuation in Rheumatoid Arthritis Patients on Long-Term Tocilizumab Treatment
نویسندگان
چکیده
منابع مشابه
Tocilizumab for the treatment of rheumatoid arthritis.
Tocilizumab is a humanized anti-IL-6 receptor monoclonal antibody, which binds to circulating soluble IL-6 receptor and membrane-expressed IL-6 receptor, inhibiting IL-6 binding to both forms of IL-6 receptor. Several Phase III clinical trials demonstrate the clinical efficacy of tocilizumab as monotherapy or with disease-modifying anti-rheumatic drugs for adult patients with moderately to seve...
متن کاملTocilizumab for the treatment of rheumatoid arthritis
Tocilizumab (TCZ) is a humanized monoclonal antibody against the IL‐6 receptor, approved in Japan, Europe and the USA for the treatment of severe rheumatoid arthritis. Several Phase III trials have shown a clinical efficacy of TCZ, such as in treatment of rheumatoid arthritis patients with no previous methotrexate failures both in combination with methotrexate and in monotherapy (the AMBITION t...
متن کاملThe effect of combined antioxidant supplement on serum lipids levels in female Patients with rheumatoid arthritis
Background: Rheumatoid arthritis (RA) is one of the autoimmune diseases with unknown etiology that its prevalence in females to males is 3 to 1. This disease has positive relationship with occurrence of atherosclerosis and cardiovascular diseases are taken into account for 50% of death in RA. Regarding the recent researches, antioxidant supplements may have important role in serum lipids reduct...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2018
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2018/2453265